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Using several hormones in low doses and incorporating lifestyle interventions might maximize the clinical effect while minimizing the side effects. Clearly, many patients would find daily injections of hormones preferable to undergoing bariatric surgery, even if these injections would need to be continued in the long-term to keep the weight off
This helps them make informed choices and work toward effective long-term weight control
Exploratory analyses highlighted a link between treatment with tirzepatide and amelioration of biomarkers associated with inflammation and atherosclerotic cardiovascular diseases [84]
A co-primary analysis compared dual therapy versus GLP-1 RA monotherapy (N = 13,782 matched pairs after 1:1 propensity score matching) to assess whether the combination confers incremental benefit beyond GLP-1 RA alone
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