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Once the bottle of methyl crystals and the sterile saline is opened and mixed, the sterile integrity of the (now fluid) B12 can no longer be guaranteed and is therefore potentially open to contamination

Vitamin B-12 has garnered attention for its potential benefits in weight loss, and its role can be particularly impactful when combined with other treatments

Medications like omeprazole, cimetidine, lansoprazole, and folate can interfere with B12 absorption

They will also set an upper limit on the total weekly dose (for example, some experts recommend not exceeding approximately 300 mg per week in subcutaneous dosing without further evaluation) to minimize any risk of adverse effects