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Research published in Neuro Endocrinology Letters explored Epithalons influence on melatonin secretion and its role in the neuroendocrine system in animal models
At the microbial level, taxa such as Lactobacillus and Bifidobacterium favour TRP availability for 5-HT synthesis, whereas enrichment of pro-inflammatory Proteobacteria enhances immune-driven IDO activation and KYN production [175], directly linking microbial ecology to mood-relevant neurochemical pathways
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