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Common side effects may include: nausea vomiting diarrhea constipation abdominal discomfort decreased appetite These effects are one reason the medication is increased gradually over time

Metabolic and cardiometabolic markers that may reflect the drug's activity include: Fasting blood glucose and HbA1c (particularly relevant in type 2 diabetes) Lipid profile (total cholesterol, LDL, triglycerides) Blood pressure Waist circumference Liver function tests, particularly in patients with metabolic dysfunction-associated steatotic liver disease (MASLD, previously termed NAFLD)

An initial consultation establishes injury history, inflammatory markers, and organ function before any protocol is designed

For example, in tendon fibroblast cells, BPC-157 dramatically increases phosphorylation (activation) of FAK and paxillin, leading to more cell migration and survival at injury sites