This months blog is focusing on what I consider the most important molecule for detoxifying, Glutathione (GSH)
L-carnitine is the predominant carnitine used in biological and medical fields and is commonly referred to as carnitine. The human body contains about 300 mg/kg of L-carnitine, 98% of which is intracellular, with 80% present in the muscles, 510% in the gastrointestinal tract, and 3% in the liver ( Endogenous Synthesis and Exogenous Sources In the average adult diet, it is estimated that about 75% of the daily carnitine requirement mainly comes from meat, fish, and dairy products (Figure 1) (Figure 1) ( Figure 1 The distribution and homeostasis of carnitine within the body is controlled by organic cationic transporters (OCTN) ( in vivo ( Biological Functions Transport of Long-Chain Fatty Acids Into the Mitochondrial Matrix The essential function of carnitine is to transport LCFAs from the cytoplasm to the mitochondrial matrix for subsequent degradation by -oxidation, known as carnitine shuttle ( The carnitine shuttle has three main steps
For example, GLP-1 Peptides (like semaglutide): Used for blood sugar management and major weight loss
We generally suggest patients stop taking ACE inhibitors, angiotensin receptor blockers or direct renin inhibitors 24 hours before undergoing anesthesia to reduce the risk of your blood pressure falling too low when combined with anesthesia
