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2014;4:e232
It won't manage a severe IBD flare
In practical terms, the difference is small enough that standard dosing protocols do not adjust for it
CB-839 resistant breast cancer cell line (but not their parental cells) showed down-regulated glutamine consumption and requires exogenous asparagine in cell culture medium for proliferation, implying glutamine independence in cancer cells may be related to the switch to asparagine pathway in order to reach the cellular demand for survival [65]
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