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Science 378 , 276284 (2022)
[PMID: 36685285] PubMed record related to this compound for laboratory literature review
7 In fact, xCT is considered to be the main transporter of cystine in cancer (Table 1) 25,26,27 and its expression is controlled by nuclear factor erythroid 2-related factor 2 (NRF2), a master regulator of the cellular redox state, 28 highlighting the importance of xCT in an oxidative stress-resistant cancer cell phenotype
Their main role is to neutralize free radicals which damage the cells and increase the bodys defence mechanism by boosting immunity
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