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Fatigue on tirzepatide and semaglutide-related fatigue can create a cycle where poor sleep worsens digestive symptoms, digestive discomfort disrupts sleep further, and the combined effect makes side effects harder to tolerate

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Who might it be best for Given the mechanism, benefits and limitations, the ideal candidate profile might look like this: Individuals who have stubborn fat (especially visceral/subcutaneous) despite diet/exercise efforts, and want to improve body composition without major muscle loss

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