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Emerging antiobesity drugs in development Numerous novel treatments for obesity are currently in the pipeline, including triple agonists that target GLP-1, GIP, and glucagon receptors [26]
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FIGURE 6 Moreover, in vitro Western blotting further revealed a decrease in Nrf2 and HO-1 protein levels in HBZY-1 cells exposed to Gd-IgA1, with the subsequent reversal of these alterations upon Lut treatment (Figures 6D,E)
Emerging evidence suggests that GLP-1 receptor agonists can suppress dopamine signaling in reward circuits, effectively lowering the volume on cravings ( PMC , 2024)
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