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Including an L-Carnitine supplement in your dietary pattern helps you turn fatty acids into energy, reduce muscle fatigue, and increase exercise performance and endurance.
Researchers and clinicians using it do so based on extrapolation from animal data and accumulating clinical experience rather than proven efficacy in humans
The clinical consequence is most significant for drugs with narrow therapeutic indices where a 20 to 40% reduction in Cmax translates to subtherapeutic exposure
While this is a necessary first step, it frequently creates highly reactive, electrophilic intermediate metabolites that are actually more toxic and dangerous than the original parent compound
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