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Nevertheless, the authors do point out that they cannot rule out a positive effect on a small subgroup of patients, or an effect of UA occurring earlier in the neurodegenerative process

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At the end of the run-in period, patients who remained inadequately controlled (HbA1c between 7% and 10%) were randomized to either SOLIQUA 100/33 (n=469), insulin glargine 100 units/mL (n=467), or lixisenatide (n=234)