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The peptide upregulates tyrosinase, but the enzyme requires UV-induced oxidative stress to catalyze melanin polymerization
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Metformin: After administration of a single oral metformin HCl 500 mg immediate-release tablet with food, geometric mean metformin Cmax and AUC differed less than 5% between pediatric type 2 diabetic patients (12 to 16 years of age) and gender- and weight-matched healthy adults (20 to 45 years of age), all with normal renal function
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