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Additional hormone replacement can make these results more noticeable
To further support the impact of CBS on replenishing GSH levels under cystine-restricted conditions, we expressed a codon-optimized CBS (CBS OPT ), which is resistant to the designed sgRNA (Fig
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Excessive activation of the ionotropic and metabotropic glutamate receptors by Hcy exacerbates excitotoxicity, leading to intracellular calcium overload, mitochondrial dysfunction, and apoptosis
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