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Therefore, iron metabolism imbalance, primarily driven by iron overload, is regarded as a critical driver of ferroptosis
DPP-4 inhibitors can on the other hand also be combined with an oral therapy with a SGLT-2 inhibitor (in dual combination when metformin is contraindicated or not tolerated or in triple therapy with metformin)
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A pharmacological approach targeting many MetS components and extensive gene and miRNA Therapy management may be necessary for high-risk people
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