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allopurinol undergoes metabolic conversion to alloxanthine, which is a potent xanthine oxidase enzyme inhibitor
The MTHFR enzyme creates the methylfolate
Considerable number of scientific investigations also demonstrated that exposure to AFB1 could disrupt the expression of ERK, PKC- , COX-2, caspases3/7/9, ASK1, SAPK, STAT3, E2FA, MYC, Bax/Bak, PUMA, CDKN1A, p21 , DNA/RNA polymerases, PLK, MAPK , and TRPs signaling pathways (288291)
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