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As a result, the release of IL-1, IL-6 and TNF- in the colon is reduced, the expression of tight junction proteins is increased, the integrity of the intestinal barrier is maintained, and the symptoms of UC mice are improved

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doi: 10.1016/j.jplph.2014.12.014 4 ChenI

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This observation suggests that the drugs effects might vary depending on the specific substance involved

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