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A non-surgical, non-invasive weight loss alternative like the Spatz3 adjustable gastric balloon may be worth considering
Metformin is also known to cause stomach-related side effects, such as diarrhea, which can affect appetite and food intake
Gastrointestinal disorders, primarily nausea, were the most common treatment-emergent adverse events, which could be mitigated with slower dose escalation
58 Even after a 17-week off-treatment follow-up period post-trial, while some weight regain occurred (~7%) and some metabolic benefits diminished, significant net improvements compared to baseline remained
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