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Combining Zepbound with other weight-loss medications (prescription, over-the-counter, or herbal) should be avoided, as these combinations have not been studied for safety or efficacy
Many patients take high-dose B6 for conditions (PMS, morning sickness, carpal tunnel) that either no longer apply or have better-supported treatments
Approval requires documented medical necessity, BMI thresholds (typically 27+ with comorbidities or 30+), and trial of metformin or other diabetes medications
Appetite suppression is working consistently throughout each week
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