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Campisi, M
Under the conditions of exposure to low-intensity light at night and circadian disruption that only suppresses nocturnal melatonin production, both the Warburg effect and the uptake of LA and its metabolism to 13-HODE in breast cancer xenografts become completely arrhythmic and operate at a constitutively high level throughout the entire day (all 24-hrs).[ref][ref] Let me point out here that melatonin production decreases with age and cancer rates increase with age There is a lot of epidemiological evidence tying cancer rates especially breast and prostate cancer to exposure to light at night, which decreases peak melatonin production
Centella Asiatica complex (including Madecassoside and Asiaticoside) soothes irritation and supports skin repair , while Ceramide NP rounds out the formula by fortifying moisture retention for lasting hydration
None of this is surprising, since oxidative stress is closely linked with other forms of aging as well
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