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This steadier state may reduce nausea or other dose-related side effects in some patients, though clinical evidence specifically comparing twice-weekly to once-weekly schedules is limited
The approved dosing regimen begins at 0.25 mg once weekly for four weeks (an initiation dose to improve tolerability), then increases to 0.5 mg once weekly, with further increases to 1 mg or 2 mg if needed for glycaemic control
The vegetarian and vegan challenge: dietary L-carnitine intakes are 5 to 30 times lower in these diets
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