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PMID 19127265
Our work herein identifies a key role for MC-derived histamine release and subsequent H4R activation in driving clinical and histopathologic severity in UC-like inflammation by regulating innate neutrophil recruitment and associated mucosal injury, likely via coordinating the downstream local production of IL-6 and neutrophil-attracting chemokines
Isoprostanes, novel markers of oxidative injury, help understanding the pathogenesis of neurodegenerative diseases
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