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Evidence-based addiction treatmentspsychological interventions and licensed pharmacotherapiesremain the standard of care in the UK
Wegovy (semaglutide 2.4 mg) is FDA-approved for chronic weight management in patients with obesity (BMI 30) or overweight (BMI 27) with at least one weight-related comorbidity, and since 2024 for cardiovascular risk reduction in patients with established cardiovascular disease and overweight or obesity
Randomized controlled trial of oral glutathione supplementation on body stores of glutathione Aebi S., et al (1991)
Early research and growing examples suggest that addressing both hormonal decline with MHT and metabolic changes with GLP-1 therapy could result in greater weight loss and metabolic improvements compared to either approach alone
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