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acetylation polymorphism represents one of the oldest and most intensively studied pharmacogenetic traits and refers to hereditary differences concerning the acetylation of drugs and toxicants
GLP-1R surface expression and internalisation assays by high-content microscopy The assays were performed as previously described (12)
Our observation of only a tendency for reduced -arrestin 2 recruitment at the phospho-null mutant receptor is also in agreement with a previous report highlight the biphasic mode of -arrestin 2 GLP-1R interaction, with a phosphorylation-independent as well as a phosphorylation-dependent component (28)
Proper storage of semaglutide is essential to ensure its effectiveness and safety
