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A 72-week trial carried out on Wegovy found that patients using the 7.2 mg maintenance dose achieved, on average, a change in body weight of 21% compared to 2.4% in the placebo group
The SELECT trial, which supports the expanded indication, enrolled patients 45 years of age and older with pre-existing cardiovascular disease and a body-mass index of 27 or greater without diabetes
An important note: Remember that you lose a substantial amount of weight, you may need a reduction in your dose of thyroid hormone replacement medication
Metabolic diseases In addition to muscle and neurodegenerative conditions, alterations in NAD + levels and mitochondrial homeostasis are also observed in aging-associated metabolic diseases, particularly those conditions impacting highly mitochondrially-active tissues such as the kidney and liver 292,293,294
