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Concentration and formulation considerations Higher concentration solutions generally absorb better because they maintain a stronger concentration gradient across the mucosal membrane
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However, TXNs display many differences from the host thioredoxins, and are considered to be unique proteins of trypanosomatids and appropriate targets for anti-parasite drug design (Comini et al., 2 to redox pathway that include cTXNPx, mTXNPx, and nsGPx-I involving thiol/disulfide exchange (reviewed in Arias et al., T
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