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A metallic taste during the infusion is equally harmless

Balleine, Distinct opioid circuits determine the palatability and the desirability of rewarding events

Acknowledgments The authors wish to thank Mohammad Yassine, BPharm, MSc and Racha Aaraj, Pharm D, MSc, MPH from Phoenix Clinical Research for the support in the preparation of this manuscript

NEJM 2022 Frequently Asked Questions Dysesthesia is abnormal touch sensation tingling, numbness, or "pins and needles." It affects 20.9% of retatrutide users at the 12mg dose versus less than 1% on placebo