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Journal of Physiology , 596(17), 4011-4025
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In a substudy of 178 patients from the SUSTAIN 8 trial on semaglutide as a diabetes treatment, the average proportion of lean mass loss was nearly identical at 40%, despite lower doses and less total weight loss than in the STEP 1 trial
Although statistically significant, these effects remain smaller than those achieved with retinoids or growth factor formulations
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