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[9] Pharmacodynamic Interaction Assessment A pharmacodynamic (PD) interaction occurs when two agents affect the same physiological target or downstream pathway, producing additive, synergistic, or antagonistic effects even without altering each other's concentrations
The results were from a phase 2, 52-week double blind dose-ranging study of once-daily semaglutide versus placebo and liraglutide 3 mg as active control
In a separate study of people with heart disease, Wegovy reduced the risk of major cardiovascular events by 20%
Novak M et al
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