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Final Thoughts AOD-9604, semaglutide, and tirzepatide all live in metabolic research, but they're three different tools for three different questions: direct adipose lipolysis versus single- and dual-incretin signaling
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In vitro , liraglutide dose-dependently downregulates pro-inflammatory mediators such as Mcp-1 and Cd38 in LPS-activated RAW264.7 macrophages, while simultaneously upregulating Erg-2, an M2-specific transcription factor (Yu et al., 2019)
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