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Ipamorelin stimulates the pituitary through growth hormone secretagogue receptors, mimicking the action of ghrelin
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NHS availability Both medications are available through NHS specialist weight management services (Tier 3 and Tier 4), but access remains limited: Eligibility for specialist services typically requires a BMI of 35 or above (or 30 or above with weight-related health conditions) Previous documented attempts at weight loss are usually required Waiting times vary significantly by region From April 2026, some GP practices can also prescribe Mounjaro for weight management, though this rollout is phased and starts with the highest clinical need (for example, a BMI of 40 or above with several weight-related conditions) Given these limitations, many eligible patients opt for private treatment
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