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By 4 weeks post-therapy, the number and FcR1 expression of peritoneal mast cells significantly declined, and this was confirmed in vitro in FAHF-2treated MC/9 cells [40]

FIGURE 5 3.6 FOXO4-DRI promotes apoptosis in senescent cells As established in prior research, FOXO4-DRI competitively binds to p53 with high affinity, thereby disrupting its nuclear interaction with FOXO4

As we will explore, the combination may offer something neither achieves alone

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