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Dose adjustment is required in moderate-to-severe renal impairment and in moderate hepatic impairment, and the medication is not recommended in severe hepatic impairment or end-stage renal disease
Pfizers danuglipron and other oral peptides aim to combine the clinical benefits of GLP-1 with the convenience of oral administration - potentially increasing patient adherence and uptake
It is common among the aging population and significantly associated with colon cancer, hepatic encephalopathy, and stroke (2)
The longer-chain alcohols pentanol, hexanol, heptanol, and octanol are increasingly insoluble in water
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