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Over-the-Counter Helpers: Antacids: If the burps are accompanied by heartburn or indigestion, an antacid might offer some relief

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The above phenomenon can be explained by the fact that the down-regulation of MITF expression will cause the down-regulation of TYR, TRP-1 and TRP-2, thereby inhibiting the synthesis of melanin, so the lower MITF expression will cause white plaques in patients with vitiligo