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Its primary mechanism is VEGF upregulation, the growth of new blood vessels that supply oxygen and nutrients to injured tissue, alongside nitric oxide pathway modulation and fibroblast stimulation in tendon and ligament tissue
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& Kosik-Bogacka, D
Loren Pickart, who first isolated GHK from human plasma albumin in 1973, documented its activity across fibroblast culture and wound healing studies over several decades
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