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To obtain stable SLC25A39 knockdown cells, Huh7 cells were transfected with lentivirus carrying a shRNA targeting SLC25A39 (shRNA-SLC25A39, 5-GTGGTTACCTCTCTCTTCATG-3) or negative control (sh-NC, 5-TTCTCCGAACGTGTCACGT-3)
[PMID: 21517776] PubMed record related to this compound for laboratory literature review
GSH depletion seemed to produce contradicting effects in our study
This dual-hit design increases the pathophysiological signal (HIF-1, TGF-, IL-1/IL-10, bacterial load) and improves reproducibility of the inflammatory/ulcerative phenotype in rats, allowing more sensitive detection of treatment effects
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