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Mid-morning snack (130 cal, 15g protein): Three-quarters cup plain Greek yogurt with one tablespoon ground flaxseed

DIRECTIONS FOR FUTURE RESEARCH The clinical use of GLP-1RAs and dual GIP/GLP-1RAs has risen sharply in recent years, driven by their proven efficacy in managing T2DM and obesity

High levels of leptin, which are common in individuals with obesity due to leptin resistance, fail to properly signal satiety, leading to continued food intake and reduced energy expenditure [32]

A systematic review and meta-analysis of randomized controlled trials found that probiotics reduced whole-gut transit time by roughly 12.4 hours and increased stool frequency by about 1.3 bowel movements per week compared with placebo, with Bifidobacterium lactis strains showing the clearest benefit