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However, if modified (PEGylation or ligand-functionalization), PLGA nanoparticles could escape the RES clearance, allowing longer systemic plasma half-life and accumulation in the CNS 99
This probably contributes to concentration of the lipid peroxidation products to be the highest in the lenses with early nuclear cataract
Its application is also expanding in clinical nutrition and infant formulas, giving the market a broad base
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