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More recently, a study presented at the annual meeting of the American Academy of Orthopaedic Surgeons (AAOS) in March 2026 indicated an increased risk of osteoporosis and osteomalacia (bone softening) after five years of taking GLP-1s
These ones, which are naturally produced in our cells, are called endogenous peptides
Importantly, the effect is most pronounced in proximal colon cancers, a region historically less protected by screening alone
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