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Your glutathione levels may be lower than recommended if you have a chronic illness or are in poor health, and the levels also may have decreased with aging (Ballatori et al., 2017

Therefore, it is not clear whether GLP-1 RA directly improves mitochondrial function, reduces ER stress, and reduces neuroinflammation, or indirectly improves these mechanisms by lowering blood glucose and improving IR

Therefore, in clinical practice, close monitoring of blood glucose levels is recommended for individuals with diabetes, particularly those receiving combination antidiabetic therapy or during the early phase of dose adjustment