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Research has shown that High-dose intravenous methylprednisolone, commonly used in MS management, can lead to decreased levels of vitamin B12 and folate in the cerebrospinal fluid and serum of MS patients [147]
When adverse effects occur, they may include mild skin reactions, gastrointestinal disturbance, or headache, typically following high-dose intramuscular injections rather than oral supplementation
Taking B12 supplements along with B6 and folic acid can significantly lower your risk
However, medical supervision helps ensure optimal dosing, appropriate monitoring, and safety when using multiple compounds simultaneously
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