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Reducing Pain: The growth factors in PRP can stimulate tissue regeneration and reduce pain in the shoulder joint

The strongest association signals for baseline GR/HGA were within a locus on chromosome 7 containing two central genes: TAC1 (protachykinin-1) that has been linked to depression and anxiety 85 and ASNS (asparagine synthetase [glutamine-hydrolyzing]) that is an important enzyme, the deficiency of which leads to substantial neurodevelopmental deficits 86

2 Table 2 Clinical Manifestations of Vitamin B12 Deficiency Maternal vitamin B 12 deficiency during pregnancy or while breastfeeding may lead to neural tube defects, developmental delay, failure to thrive, hypotonia, ataxia, and anemia

doi: 10.1016/j.cell.2017.11.048 163 ChenXKangRKroemerGTangD