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Although reported AEs are generally not serious and safety and efficacy in older adults are generally comparable to those in younger adults [36], higher AE rates may nonetheless predispose older adults to additional risks that are more critical in this population, such as hypoglycemia, dehydration, or impaired renal function
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PPO mice model was established by feeding with high-fat diet for 16 weeks, and then injected with semaglutide (30 nmol/kg -1 d -1 , sc.) for 22 days before pregnancy
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