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STEP 1 demonstrated that semaglutide 2.4 mg weekly resulted in mean weight loss of 14.9% over 68 weeks, compared to 2.4% with placebo
The good news: most side effects diminish or disappear within the first week as tolerance develops
Major challenges in NDDS include biocompatibility, biodegradability, immune-evasion efficacy, solubility and stability in biological environments, and the potential for off-target effects
contact your GP or trial clinician promptly for persistent palpitations or unexplained fatigue
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