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GLP-1 essentially links metabolism and neuroscience , shaping both fuel stability and reward-driven behavior

Medicaid spending on GLP-1s for all conditions increased from $597.3 million for about 755,000 prescriptions in 2019, to $3.9 billion for 3.8 million prescriptions in 2023, according to KFF

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Beyond the improved glycaemia control, essential for the short term treatment of diabetes (188), different GLP-1RAs are powerful clinical tools for the management of diabetic kidney disease (DKD) (189) non-alcoholic steatohepatitis (NASH) (190), neuroinflammation (191), obesity and cardiovascular disease (192195)