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GLP-1 plays a key role in regulating blood sugar levels by stimulating insulin release, reducing appetite, and slowing gastric emptying

Considering this evidence, we hypothesised that activation of the GLP-1 pathway in the OB activates GABAergic neurons in the LH, which inhibit PVN neurons, reducing their stimulation of preganglionic sympathetic neurons

Liraglutide: for obesity, not just type 2 diabetes Liraglutide is TGA approved as an adjunctive therapy for obesity, extending its indications for use beyond treatment of type 2 diabetes

Based on this and other reports, it is recommended that patients who overdose on semaglutide receive supportive care, including medications to prevent nausea and vomiting, correction of fluid and electrolyte imbalances, and close monitoring of blood sugar levels