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However, pro-inflammatory mediators in VF and brain are suppressed during later stages of AD, indicating that neuro-inflammation-mediated neurodegeneration occurs mainly in the early or a specific stage of AD rather than the whole clinical course (68)
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The classical forms of the disease are more severe and are likely to be diagnosed early in life, as opposed to the non-classical form, which may be confused with PCOS due to overlapping symptoms, including female infertility
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