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Reduced endothelial activation and leukocyte adhesion are particularly relevant to early vascular dysfunction

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The key values taken under consideration were R2 ( gross elasticity of the skin including viscous deformation, ratio of ability of recovery to final distension values) and R6 (portion of visco-elasticity on the elastic part of the curve, the smaller the value the higher the elasticity and the skin barrier firmness)

Data availability Data supporting the findings of this study are available within the article and its Supplementary information files or from the corresponding author upon reasonable request