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Per-Compound Adverse Events Retatrutide The Jastreboff 2023 Phase 2 trial (Jastreboff et al., 2023) and the TRIUMPH-4 Phase 3 trial (Bays et al., 2025) anchor retatrutide's safety profile
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No claims are made regarding therapeutic, diagnostic, or clinical applications
However, this phase III trial was criticized for its small sample size, short duration, and high rate of patient dropout (De La Rubia et al., 2019)
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