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We do not start therapy if you are pregnant, planning pregnancy, or have a personal/family history of medullary thyroid carcinoma (MTC) or MEN2
It is interesting to note that melanoma increases the risk of PD fourfold, and PD increases the risk of melanoma fourfold (112)
Many individuals successfully maintain weight loss through diet, exercise, and lifestyle changes alone, though research shows approximately 50% of weight returns within one year post-discontinuation for most people
Certain conditions can make its use unsafe or inappropriate: Personal or Family History of Medullary Thyroid Carcinoma (MTC): Due to the observed risk of thyroid C-cell tumors in rodent studies, individuals with this history should avoid semaglutide
