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Thereafter, membranes were washed and incubated with horseradish peroxidase-conjugated anti-IgG secondary antibody (Cell Signaling Tech, Frankfurt, DE) followed by detection using a chemiluminescence system (Pierce ECL Western Blotting Substrate, ThermoFisher) and Sapphire Biomolecular Imager (Azure Biosystems)

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The susceptibility of neurons to mitochondrial dysfunction may be explained by the high dependence of neurons on oxidative phosphorylation (69)

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